Expertise

Innovative Artery-on-a-Chip bridges cell culture and animals, advancing cardiovascular research for prevention, diagnostics, and therapy.

A perfusion platform to apply bi-modal mechanical stimulation wall shear stress (WSS) and circumferential strain to up to 12 blood vessel-on-a-chip simultaneously.

Understanding cell-cell interactions and spatial relationships in healthy or diseased organs represents a technical challenge. Single-cell genomics is powerful but lacks spatial context. In this study, automated immunolabeling has been applied to obtain a versatile multiplex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues.

A precise flow control system and micro-cannula injection method were developed to regulate atrial preload and assess cardiac function in zebrafish larvae.

This study is the first to achieve vascularization of kidney organoids in HUVEC co-culture conditions using a microfluidic organ-on-chip. This model offers valuable insights into kidney organoid vascularization and is a promising tool for studying kidney development and drug testing.

Dr. Agarwal’s Physiomimetic Microsystems Laboratory (PML) developed the microfluidic pancreas-on-chip platform that can provide controlled oxygen and perfusion environments for viability and real-time imaging.

Microfluidic 3D printing combines flow control and laser lithography to create high-resolution multimaterial structures, enabling advanced cell culture and bioprinting.

This article presents a microfluidics model to mimic skin for sudation research. Our flow controller permits a precise distribution of sweat in artificial skin.

This study introduces a microfluidic transistor, mimicking electronic behavior, enabling precise fluid control in lab-on-a-chip systems.

New 3D model for cancer investigations based on the mimicking of tumor microenvironment using pressure pump to recreate interstitial flow.