Emulating the chondrocyte microenvironment using multi-directional mechanical stimulation in a cartilage-on-chipRead more
A cartilage-on-chip platform coupled to Fluigent pressure controllers to generate compressive or multi-directional mechanical stimulations to study how mechanical stimulation of the chondrocytes can help to reproduce the native articular cartilage microenvironment.
Generation of bubbles using the RayDropRead more
Microfluidic devices are used for Bubble generation at micron-scale, yielding high monodispersity and well-controlled size. We investigated how parameters such as the geometry of the nozzle and the continuous-phase flow rate affects the microbubble formation process.
Things you should know when integrating fluidics into your systemRead more
The choice of the right method of fluid management can often determinate the success of a project, as well as the overall time and cost of manufacturing. Here is what you need to consider and be aware of when integrating fluidic control into your system.
Microfluidics Technology for the Design and Formulation of NanoparticlesRead more
Engineered Nanoparticles (NPs) are becoming essential to enhance drug delivery systems (DDSs) for both biomedical and pharmaceutical applications. Controlling the delivery of molecules of interest, increases their concentration in a desired location and lead to improved drug efficacy as well as minor adverse effects. NPs including lipid-based and polymeric NPs have been used over the years as nanocarriers of various bioactive molecules.
Interfacing ARIA with fluorescence microscopy to automate multiplexed tissue imagingRead more
Single-cell genomics is powerful but lacks spatial context, however, traditional immunofluorescence enables one to capture only two to six molecular features. Imaging technologies have been developed to address these issues, but each possesses limitations that constrain widespread use.