Microfluidics in Life Science
Microfluidics provides the ability to control cellular microenvironments with high spatiotemporal precision. It also presents cells with mechanical and biochemical signals in a more physiologically relevant context.
A new level of technology
Microscopy and cell biology
Flow cells or microfluidic chips combined with a fluid perfusion system and microscopy are compatible with several applications including DNA or RNA hybridization, drug combination and long-term perfusion, or immunostaining.
Cell culture and Organ on a chip
This area is an ideal microenvironment to study molecular and cellular-scale activities that underlie human organ function as well as identify new therapeutic targets in vitro.
Digital PCR
Microfluidic dPCR offers a new level of insight compared to quantitative PCR (qPCR). Droplet-based microfluidic is an excellent solution to partition a sample.
Want to learn more about the capabilities of microfluidics in life science? See Fluigent’s CEO France Hamber discuss microfluidic disruptive discoveries
Research applications
MICROFLUIDIC CASE STUDY – Hans-Knöll-Institut, New Antibiotics, Cultivation in Droplets – Fluigent
This project focuses on how Fluigent’s customers use microfluidics to achieve outstanding results in their technology experiments.
Our speakers are Prof. Dr. Miriam Agler-Rosenbaum (Head of Bio Pilot Plant Department), Dr. Sundar Hengoju, Dr. Dede Man from Leibniz Institut for Natural Products Research and Infection Biology (Hans Knöll Institute), to be precise – Bio Pilot Plant Department.
How are they trying to find new antibiotics? Why is this important for infection biology? How do they research natural products? What are these exactly? How does microfluidics allow them to cultivate microbes in droplets? How does the technology increase their efficiency millions of times over? In which cases pressure pumps are better than syringe pumps? How to stabilize microfluidic droplets? Watch this episode to find out. And that’s just one story told. There are many possible applications for microfluidics.
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Industrial field
Expertise & resources
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From the life sciences to the food industry, many applications require the use of fluids driven at flow rates from nanoliters to milliliters per minute. At such low flows, the success of these applications strongly depends on the level of control and automation of the fluidic operations.
These applications require flow control systems that are adapted for ensuring their success.