Microfluidic Injection Valve

[LSW001]

L-SWITCH™ 6-port/2-position

The L-SWITCH™ is a 6-port/2-position bidirectional microfluidic injection valve used to handle liquids through different valve ports. It is ideal for precise volume injection or for switching between different fluids, as it allows automation of sample injection in your fluid line.

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Main benefits

Quick
Valve actuation time
Compact
Uses minimum bench space
Biocompatibility
Biologically compatible
Accurate
Low internal volume

Features of Microfluidic Injection Valve

6-port/2-position

Peripheral ports (numbered from 1 to 6) can alternatively be connected to the right or the left channels. The L-SWITCH™ is actuated by a motor that drives a rotor – where the fluidic path is engraved – against a stator – containing the fluidic paths.

Sample injection

The L-SWITCH™ microfluidic injection valve enables one to load and inject a precise volume of fluid. By selecting the position of the L-SWITCH™ you will choose when you want to load the fluid and then inject it (using a sample loop). Several sample loops are available from 5 µL to 100 µL.

Workflow automation

The valve can be controlled by OxyGEN software for long-term experiments. Create a time-based protocol to set the actuation timing of the valve(s).

Related applications

Smart control and automation of your fluidic path

Discover Fluigent microfluidic valves, a set of compact instruments allowing to complexify and easily handle the fluidic path of your system. Once integrated in the set-up, the valves can be controlled in real-time and even without the requirement of a PC.

How to perform sample injection with the L-SWITCH microfluidic injection valve?

The L-SWITCH is a 6-port / 2-position microfluidic injection valve that, combined with Fluigent’s pressure controllers, allows us to inject a small volume of sample into a liquid stream, reducing cost, as well as to run and automate long-term experiments with high reproducibility and reliability.

The microfluidic injection valve has 6 inputs and two interchangeable configurations shown on the images below. Each input is connected to a neighbor output, either on the right or the left depending on the configuration.

Example of use

By combining the microfluidic injection valve with our cell encapsulation platform, it is possible to work with samples with a reduced volume (e.g. working with cells of limited availability, such as stem cells, primary cells from patients…). It is also ideal for the use of rare cells or expensive reagents with a total volume lower than 500µl/.

Cell encapsulation platform with a microfluidic-injection-valve

Fig 1. Cell encapsulation platform with an injection loop (L-Switch position A).

injection loop microlfuidic injection valve

Fig 2. Cell encapsulation platform with an injection loop (L-Switch position B).

Benefits of the L-SWITCH microfluidic injection valve

No overpressure: Switch between 2 flow configurations in less than 100ms
No waste: No dead volume and low carryover volume.
Biocompatible: High chemical and biological compatibility
Reproducibility and Reliability: Perform identical injections

Specifications

PERFORMANCE

Switching time	100 ms
Maximum pressure	Up to 7 bar (100 psi)

HARDWARE SPECIFICATIONS

Internal volume	660 nL
Wetted materials	PEEK
Dimensions	70 x 90 x 150 mm
Weight	475 g

CHEMICAL COMPATIBILITY

Gas compatibility	Dry, oil-free gas, air, any non corrosive or non explosive gas
Liquid compatibility	Aqueous solvent, oil, organic solent, biological sample

OxyGEN

Control in real-time, protocol automation, data record and export

ver. 2.2.0.0 or more recent

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Software Development Kit

Custom software application

ver. 22.2.0.0 or more recent

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Microfluidic Injection Valve