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M-SWITCHℱ Microfluidic bidirectional valve 

[ESSMSW003]

    11-port/10-position microfluidic valve

    The M-SWITCHℱ is an 11-port/10-position microfluidic bidirectional valve for injection or selection of up to 10 different fluids or chips. The flow is bidirectional in the valve. The device can be used as a distributor or as a selector for either multiplexing or demultiplexing purposes.

    Ask for a quoteSpecifications
    M-SWITCHℱ, Fluigent Microfluidic Bidirectional Valve
    Main benefits
    • Automation

      Valve actuation timing

    • Compact

      Uses minimum bench space

    • Quick

      Actuation & Response time

    • Accurate

      Low internal volume

    Features of the M-Switch microfluidic dual flow control valve 

    Any of the peripheral ports (numbered from 1 to 10) can be connected to the central channel, and the fluidic path created is bidirectional. The M-SWITCHℱ is actuated by a motor that drives a rotor. It can also be used with a manifold to use a single pressure pump to deliver multiple liquids and simplify setups. 

    Generating and collecting samples 

    Different concentrations of the molecule of interest can be injected into a chip generating water-in-oil droplets. The droplets can then be sorted at the outlet of the chip using the M-SWITCHℱ microfluidic bidirectional valve according to their analyte concentrations. Each step can be automated using OxyGEN software. 

    How does the 11-port/10-position system work? 

    Any of the peripheral ports (numbered from 1 to 10) can be connected to the central channel, and the fluidic path created is bidirectional. The M-SWITCHℱ is actuated by a motor that drives a rotor. It can also be used with a manifold to use a single pressure pump to deliver multiple liquids and simplify setups. 

    The M-Switch, an automated microfluidic valve  

    The microfluidic bidirectional valve can be controlled by OxyGEN software for long-term experiments. Create a time-based protocol to set actuation timing. 

    • OxyGEN

      Read more

    Smart control and automation of your fluidic path 

    Discover Fluigent microfluidic valves, a set of compact instruments that lets you complexify and easily handle the fluidic path of your system. Once integrated into the setup, the valves can be controlled in real time, even without a PC. 

    Related applications

    • Microfluidics for Droplet Generation

      Discover
    • Microfluidics for Organ-on-chip Cell culture

      Discover
    • Microfluidics for Cell Biology

      Discover
    • Microfluidics for Cell Analysis

      Discover

    Smart control and automation of your fluidic path

    Discover Fluigent microfluidic valves-: a set of compact instruments allowing users to complexify and easily handle the fluidic path of their system. Once integrated in the set-up, the valves can be controlled in real-time and even without the requirement of a PC.

    What are the benefits of this microfluidic switching valve? 

    • Fast switching time: 400ms, making it compatible with our ultra-fast flow controllers 
    • Ultra-low internal volume: 3.5”L 
    • Versatility and ease of use 
    • Multiplexing: up to 10 different fluids 

    Example uses of the M-Switch

    Automatic switching between multiple solutions while maintaining a constant flow rate 

    Many microfluidic applications require switching between multiple solutions (such as samples or buffers) while maintaining a constant flow rate during the associated experiment. In this application, one Flow EZℱ pressure channel is connected via a manifold to ten separate vials containing different aqueous solutions. Using the M-Switchℱ and Oxygen software allows for selection of a specific solution to be directed to a microfluidic device. This represents an economical way to change between fluids, as it requires only a single pressure channel and one flow sensor. 

    The microfluidic switching valve is first set to position 1, and a constant flow rate of 10”L/min is applied. A flow unit M coupled with a flowboard allows real-time monitoring of the flow rate for constant adjustment of the pressure. Then the M-switch position is changed to the next sequential position at several time points, and the measured flow-rate is recorded. 

    Microfluidic bidirectional valve
    valve position change on flow rate

    The data for each switching interval was analyzed to determine the settling time for each change of position. Although it is possible to visually identify the switching step when reading the raw Oxygen data, in all cases normal flow was re-established within 100 ms or less. It is important to note that the flow rate is always positive during the switching steps, eliminating the possibility of cross-contamination between the various solutions. 

    For more information, read our application note on this use of the microfluidic bidirectional valve. 


    “We have been using Fluigent’s M-SWITCH, amongst other accessories, including Flow EZ system flow controllers, for the past 5 years. We are pleased with its performance, especially the programmability and automation of fluid flow that relieves the user of the need to be present next to experiments that run for several hours. We found the software interface simple to use and could count on the team’s assistance for friendly recommendations and support.”

    Sivashankar Krishnamoorthy – Luxembourg Institute of Science and Technology (LIST) 

    Specifications

    PERFORMANCE

    Switching time400 ms (180°)
    Maximum pressureUp to 7 bar

    HARDWARE SPECIFICATIONS

    Internal diameter0.5 mm
    Internal volume3.5 ”L
    Dead volumeNone
    Dimensions60 x 110 x 110 mm
    Weight746 g
    Wetted materialsCTFE, UHMW-PE

    ELECTRONICAL SPECIFICATIONS

    Power consumption2 A (peak)

    CHEMICAL COMPATIBILITY

    Gas compatibilityDry, oil-free gas, air, any non corrosive or non explosive gas
    Liquid compatibilityAqueous solvent, oil, organic solent, biological sample

    OxyGEN

    Control in real-time, protocol automation, data record and export
    ver. 2.2.0.0 or more recent

    See the offer


    Software Development Kit

    Custom software application
    ver. 22.2.0.0 or more recent

    See the offer

    Sample generation & collection

    Expertise & resources

    • Product presentation videos Microfluidic Valves : SMART CONTROL and AUTOMATION of your fluidic path – Fluigent Read more
    • Microfluidics White Papers An exploration of Microfluidic technology and fluid handling  Read more
    • Technical datasheets M-SWITCHℱ Datasheet Download
    • User manuals Easy Switch Solutions User Manual Download
    • Microfluidics case studies The Hebrew University: Encapsulation and culture in 3D hydrogels for Single cell sequencing  Read more
    • Microfluidics case studies CEA/CNRS: A flow cell for nanoscopic imaging in liquid Read more

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    Accessories

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    Kits

    • M-SWITCH tubing & fitting kit

      Buy online
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