Double Emulsion Generation Pack

[O-DE-STD-PCK]

    A complete system for producing monodisperse double emulsions

    Double emulsion has an extremely diverse application potential across various industries. However, many traditional methods for its production, such as the batch method, have their limitations. Droplet-based microfluidics with the use of Raydrop, a droplet generator developed and manufactured by Secoya technologies, allows to minimize these limitations, particularly when it comes to better size distribution and mixture (1).

    The Fluigent double emulsion generation pack is a robust and complete system for producing outstanding monodispersed double emulsion in one single device.

    Its performance is coming from the combination of Fluigent’s LineUP microfluidic pumps and the RayDrop device, a breakthrough technology for high monodispersed and stable double emulsion.

    With our Double Emulsion Production Pack, you will be able to generate double emulsion with high monodispersity, precision and stability. Moreover, with our package it is possible to use both common fluids (mineral oils, fluorocarbon oils…) and specific fluids (PLGA, PLA, alginate, agarose, ...), as you can see in the application note.

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    FLUIGENT DOUBLE EMULSION GENERATION PACK
    Main benefits
    • droplet monodispersity
      High precision

      Down to 2% monodispersity

    • ICO_BFT size
      Flexible

      All types of emulsions, adjustable shell thickness

    • ICO_BFT continuous
      Robust

      Continuous production

    Features of the double emulsion generation pack

    Complete system

    With this package, you have all the components necessary to start generating double emulsions

    Dedicated protocol

    A protocol is available to assist you in setting up and starting your experiments

    Engineered solution

    We built the package with the right pressure controllers, microfluidic chips, valves to make sure you have the highest flexibility in terms of droplet size and generation rate

    Customization possible

    We can adapt the package to fulfill your needs (droplet size, generation rate)

    Double Emulsion Generation Application Note

    In this application note we have demonstrated how we can produce a robust different type of double emulsion with a single device.

    double emulsion generation
    double emulsion generation chip

    Developed and manufactured by Secoya

    Logo-Secoya

    Main products of the Double Emulsion Generation Pack

    DOUBLE EMULSION GENERATION set up
    double emulsion generation

    Specifications

    LineUp Flow EZ pressure controller (2000 mbar) x3
    LineUp LINK Module (software control) x1
    FLOW UNIT M (x2) and L (x1)
    P-CAP series 50 mL (x2) and 15 mL (x1)
    LineUp Switch EZ (x1)
    2-SWITCH x2
    Raydrop Double Emulsions x1
    dSurf x1

    Microfluidic device specifications

    DesignCo-flow focusing design
    Inputs & Outputs3 inputs, 1 output
    Types of emulsionWater-in oil-in-water and oil-in-water-in-oil double emulsion
    Double emulsion size*Shell: from 70 to 130 µm, Core: from 20 to 120 µm
    MonodispersityCV <2%
    Generation rate5 000 Hz (measured for the smallest double emulsion size) can go higher under specific conditions
    Capillaries dimensionNozzle: Core: 30 µm & ID Shell: 70 µm ID
    Output: 150 µm ID
    Wetted material continuous phasePEEK, FEP, glass, stainless steel 316L, poluimide, Viton (seal), resin (nozzle)
    Wetted material dispersed phasePEEK, FEP, Glass, resin (nozzle)
    Fluids compatibilityWater, mineral oil, fluorinated oil, ethanol, ethyl acetate, IPA, Acetone, Chloroform

    Flow Control

    PumpsFluigent Flow EZ (2000mbar)
    Flow SensorsFluigent FLOW UNIT (M & L)
    Automated valvesFluigent 2-SWITCH

    Imaging (optional)

    MicroscopeFluigent Digital high-speed microscope

    OxyGEN

    Control in real-time, protocol automation, data record and export
    ver. 1.0.0.0 or more recent

    See the offer

    Software Development Kit

    Custom software application
    ver. 21.0.0.0 or more recent

    See the offer

    Imaging

    Pixelink Capture Software

    *Depends on fluids physical properties

    **For detailed specification: download LineUP User Manuel, ESS User Manuel

    Batch methodFluigent microfluidic method
    Processmultiple step processdirect double emulsion production
    Homogeneityrandom distribution of single and double emulsionhigh homogeneity
    Particle size distributionmore than 50% ~ 2%
    Reproducibilitylowhigh
    Live particle size controlnoprecise
    Continuous (in line) productionnoyes

    How to produce double emulsions

    Master the double emulsions production

    Expertise & resources

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