The RayDrop is a microfluidic droplet generator composed of three main parts fully removable: two inserts on each side and a center section containing a nozzle and an outlet capillary. There are four standard microfluidic connections, two on the box for the continuous phase, and one on each insert for the dispersed phase entry and the mixed phase or droplets exit.
The RayDrop works as a co-flow focusing principle. The nozzle and outlet capillary are aligned in continuous phase chamber, the dispersed phase comes through the nozzle to create the microparticles into the continuous phase and exit by the outlet insert.
40 µm to 130 µm
Ease of use
up to 10 000 Hz
no coating/surfactant needed
PLGA microparticle synthesis
Inlet and outlet capillaries: 150µm ID
Nozzle: 30µm ID
Dimensions: L *w * h = 60mm * 40mm * 13 mm
Weight: 205 g
Part Number: 1DPRD01
“My team has started using the Fluigent microfluidic kit for making polymer based particles. We tried different microfluidic systems in the past but unfortunately they were not suitable for our application. The main issue was chip blockage which rendered the process quite laborious.
The RayDrop microfluidic chip from Fluigent gave us the best results with a better control over the process.
I have to mention the excellent technical support from Fluigent, their team visited my lab 3 times to deliver training and help to optimize the process”
Dr Omar QUTACHI
Senior Lecturer in Pharmaceutics
Health and Life Sciences
De Montfort University , The Gateway, Leicester
As chemicals, can be used ethylacetate, ethanol or IPA. (The nozzle material is not compatible at long-term use with dichloromethane)
Yes, we recommend filtering all solutions before starting your experiment. The presence of dust can block the nozzle.
Leaks can sometimes appear if the fluidic connectors are not tightened enough.
Check that all the connectors are attached firmly.
(Be careful not to over tighten or your tubing may be blocked by pinching)
If the RayDrop has been manipulated (for cleaning or maintenance) the four screws might not be tightened enough.
Use an allen key to tighten.
Make sure that all tubing is well flushed before connecting the RayDrop.