Nanoparticle Production Pack

[O-MIX-LIPO-PCK] or [O-MIX-PLGANP-PCK]

A complete system for producing Nanoparticles in a reproducible manner.

The Fluigent Nanoparticles Production Pack is a robust and complete system for precise and long-term production of nanoparticles with high flexibility in terms of particle size range. The pack includes Fluigent’s LineUP microfluidic pumps and Secoya's RayDrop device- a breakthrough in technology for high-quality particle production.

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Main benefits

High precision
< 2% CV
Flexible
Adjustable particle size
Robust
Continuous production

Features of the Nanoparticle Production Pack

Complete System

With this package, users have all the components necessary to start generating nanoparticles with high monodispersity and high stability.

Dedicated Protocol

A protocol is available to assist users in setting up and starting your experiments

Download the protocol

Engineered Solution

We built the package with the right pressure controllers, microfluidic chips, and valves to make sure you have the highest flexibility in terms of particle size and generation rate

Customization Possible

We can adapt the package to fulfill your needs (particle size, generation rate)

Related applications

nanoparticle PRODUCTION chip fluigent raydrop

Developed and manufactured by Secoya

Main Products of the Nanoparticle Production Pack

With the components of the nanoparticle production pack, users can produce nanoparticles with high monodispersity. This pack controls the size of the nanoparticles, increasing the range of applications in which they can be used.

_{Figure 1 : Liposome Production Station Setup [O-MIX-LIPO-PCK]}

*_{Figure 2 : PLGA Nanoparticle Production Station Setup [O-MIX-PLGANP-PCK]}*

Specifications

LineUp Flow EZ pressure controller (2000 mbar) x2

LineUp LINK Module (software control) x1

FLOW UNIT M (x1) and L (x1)

P-CAP series 15 mL (x3)

LineUp Switch EZ (x1)

2-SWITCH x2

Raydrop Single Emulsions x1

SWITCH EZ x1

Liposome Nanoparticles Production

Inner phase	Absolute ethanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL
Outer phase	Phosphate-buffered saline (PBS) (pH 7.2)
Particle size range	30 nm to 150 nm
Polydispersity	From 7% to 15%

PLGA Nanoparticles Production

Inner phase	Acetone + Poly(lactic-co-glycolic acid) (PLGA) Resomer 756 1%hanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL
Outer phase	Deionized water + Polyvinyl alcohol (PLGA) Mw 90000 – 10000 80 % hydrolyzed
Particle size range	100 to 250 nm
Polydispersity	From 5% to 15%

Flow Control

Pumps	Fluigent Flow EZ (2000mbar)
Flow Sensors	Fluigent FLOW UNIT (M & L)
Automated valves	Fluigent 2-SWITCH

Imaging (optional)

Microscope

Fluigent Digital high-speed microscope

OxyGEN

Control in real-time, protocol automation, data record and export

ver. 1.0.0.0 or more recent

See the offer

Software Development Kit

Custom software application

ver. 21.0.0.0 or more recent

See the offer

Imaging

Pixelink Capture Software

	Extrusion method	Fluigent microfluidic method
Particle size distribution	up to 50%	~ 2%
Reproducibility	low	High
Particle size control	no	Precise
Continuous (in line) production	no	yes

Nanoparticle Production Pack