Nanoparticle Production Pack

[O-MIX-LIPO-PCK] or [O-MIX-PLGANP-PCK]

    A complete system for producing Nanoparticles in a reproducible manner.

    The Fluigent Nanoparticles Production Pack is a robust and complete system for precise and long-term production of nanoparticles with high flexibility in terms of particle size range. The pack includes Fluigent’s LineUP microfluidic pumps and  Secoya's RayDrop device- a breakthrough in technology for high-quality particle production.

    ALGINATE BEAD GENERATION PACK fluigent
    Main benefits
    • droplet monodispersity
      High precision

      < 2% CV

    • ICO_BFT size
      Flexible

      Adjustable particle size

    • ICO_BFT continuous
      Robust

      Continuous production

    Features of the Nanoparticle Production Pack

    Complete System

    With this package, users have all the components necessary to start generating nanoparticles with high monodispersity and high stability.

    Dedicated Protocol

    A protocol is available to assist users in setting up and starting your experiments

    Engineered Solution

    We built the package with the right pressure controllers, microfluidic chips, and valves to make sure you have the highest flexibility in terms of particle size and generation rate

    Customization Possible

    We can adapt the package to fulfill your needs (particle size, generation rate)

    nanoparticle PRODUCTION chip fluigent raydrop

    Developed and manufactured by Secoya

    Main Products of the Nanoparticle Production Pack

    With the components of the nanoparticle production pack, users can  produce nanoparticles with high monodispersity. This pack controls the  size of the nanoparticles, increasing the range of applications in which they can be used.

    Figure 1 : Liposome Production Station Setup [O-MIX-LIPO-PCK]
    Figure 2 : PLGA Nanoparticle Production Station Setup [O-MIX-PLGANP-PCK]

    Specifications

    LineUp Flow EZ pressure controller (2000 mbar) x2
    LineUp LINK Module (software control) x1
    FLOW UNIT M (x1) and L (x1)
    P-CAP series 15 mL (x3)
    LineUp Switch EZ (x1)
    2-SWITCH x2
    Raydrop Single Emulsions x1
    SWITCH EZ x1

    Liposome Nanoparticles Production

    Inner phaseAbsolute ethanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL
    Outer phasePhosphate-buffered saline (PBS) (pH 7.2)
    Particle size range30 nm to 150 nm
    PolydispersityFrom 7% to 15%

    PLGA Nanoparticles Production

    Inner phaseAcetone + Poly(lactic-co-glycolic acid) (PLGA) Resomer 756 1%hanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL
    Outer phaseDeionized water + Polyvinyl alcohol (PLGA) Mw 90000 – 10000 80 % hydrolyzed
    Particle size range100 to 250 nm
    PolydispersityFrom 5% to 15%

    Flow Control

    PumpsFluigent Flow EZ (2000mbar)
    Flow SensorsFluigent FLOW UNIT (M & L)
    Automated valvesFluigent 2-SWITCH

    Imaging (optional)

    MicroscopeFluigent Digital high-speed microscope

    OxyGEN

    Control in real-time, protocol automation, data record and export
    ver. 1.0.0.0 or more recent

    See the offer


    Software Development Kit

    Custom software application
    ver. 21.0.0.0 or more recent

    See the offer

    Imaging

    Pixelink Capture Software

    Extrusion methodFluigent microfluidic method
    Particle size distributionup to 50%~ 2%
    ReproducibilitylowHigh
    Particle size controlnoPrecise
    Continuous (in line) productionnoyes