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Microfluidic Flow Control System

  • Customize your own

MFCS™ series

The MFCS™, or Microfluidic Flow Control System, is a pressure based microfluidic flow controller. Either 4 or 8 channels are available with different pressure ranges for  microfluidic experiments. By using the patented FASTAB™ microfluidic technology, the MFCS™ generates a constant pressure-driven flow rate that allows for reliable and repeatable experiments.

Ask for a quoteSpecifications
microfluidic flow control system
Main benefits
  • Customizable

    Integrate a pressure/vacuum source

  • Adaptable

    Up to 8 channels with various ranges

  • Reliable

    Patented & Field-proven technology

  • compact
    Compact

    Flat & Light design for benchtop use

Features of the MFCS

Easy to set up & use

The Microfluidic Flow Control System can be controlled by Fluigent software to automate your protocols. It can easily be connected to other microfluidic devices such as FLOW UNIT sensors to allow for flow-rate control. 

Independent channels

Each channel can be controlled independently and deliver a specific amount of pressure or vacuum to handle fluids. Available pressure ranges from -800 mbar for vacuum aspiration up to 7 bar for pressure. 

Get superior results fast

Reach your pressure targets rapidly and get your experiment started instantaneously. The field-proven technology lets you quickly obtain reliable and superior results for your experiments. 

Reliable & Reproducible results

The FASTAB™ microfluidic patented technology used by the MFCS™ Microfluidic Flow Control System series avoids cross-contamination as there is no direct contact between the instrument and the reagents. The pulseless and precise control enabled by our pressure-driven technology is critical for repeatable results in many applications. 

Adaptability & Integration

The MFCS™ system can provide negative or positive pressures as needed by using up to four or eight independently controllable channels. In addition, a microfluidic pressure pump can easily be integrated into a setup with the Software Development Kit (SDK). 

Fully customizable

The design of our Microfluidic Flow Control System depends on your needs. You can choose the number of channels in the device (4 or 8), with each channel ranging from -800 mbar to 7 bar, and you even have the option to integrate a pressure or vacuum source inside the instrument. Customize your controller to meet your control needs. 

Related applications

  • Microfluidics for Droplet Generation

    Discover
  • Microfluidics for Organ-on-chip Cell culture

    Discover
  • Microfluidics for Cell Biology

    Discover
  • Microfluidics for Cell Analysis

    Discover
Fluigent software
FLOW UNIT sensors

Pressure-based microfluidic controller: Better stability & responsiveness  

The MFCS™ series product range is the first generation of microfluidic systems. Along with the MCFS™-EZ or MCFS™-EX, a manifold can be added to redirect pressure to multiple fluid reservoirs. 

The flow generated can be measured or controlled with FLOW UNITs and the Flowboard. The MFCS™-EX provides up to 8 negative or positive pressure channels to pressurize multiple fluid reservoirs. It can have an integrated pressure/vacuum source or be coupled with the FLPG+, an external pressure source, for those who don’t have access to a laboratory bench-mounted gas source. The Microfluidic Flow Control System can be integrated, automated or controlled in real time using Fluigent Software Solutions. 

The technology used in this pressure pump avoids cross-contamination because liquids only contact air. The pulseless flow provides improved reliability and reproducibility of results. The use of pressure to handle fluids also provides a quick response time allowing for precise operations such as stop flow and accurate pressure/flow rate steps. The MFCS™ series products are well suited to manipulating fluid volumes in the low to sub microliter per minute range. 

Specifications

PERFORMANCE

Output pressure stabilityHighly monodispersed droplet size – No oscillation
System settling timeNo transitory regime – Reagent saving – Stop-flows
VolumesWide range of volume can be controlled – No compromise between volume and stability
FlexibilityAny mix or pressure ranges are available – Highly customizable

PRESSURE/VACUUM RANGE

Channel part number (MFCS™-EZ)Channel part number (MFCS™-EX)Pressure/Vacuum rangeRequired supply
EZ-00345001EX-003450010 to 345 mbar (0 to 5,00 psi)1100 mbar (15,95 psi)
EZ-01000001EX-010000010 to 1000 mbar (0 to 14,50 psi)1100 mbar (15,95 psi)
EZ-01000002EX-010000020 to 2000 mbar (0 to 29,01 psi)2100 mbar (30,46 psi)
EZ-07000001EX-070000010 to 7000 mbar (0 to 101,5 psi)7100 mbar (103,0 psi)
EZ-80025001EX-800250010 to -25 mbar (0 to -0,36 psi)-800 mbar (-11,6 psi)
EZ-80069001EX-800690010 to -69 mbar (0 to -1,0 psi)-800 mbar (-11,6 psi)
EZ-80345001EX-803450010 to -345 mbar (0 to -5,00 psi)-800 mbar (-11,6 psi)
EZ-80800001EX-808000010 to -800 mbar (0 to -11,6 psi)-800 mbar (-11,6 psi)

HARDWARE SPECIFICATIONS

DimensionsMFCS™-EZ: 160 x 230 x 63 mm
WeightMFCS™-EZ: 2.0 kg (4.4 lbs)
Output connectorsFemale luer lock (-800 to 2000 mbar) – 4mm OD tube (7 bar)

ELECTRONICAL SPECIFICATIONS

Power consumption1.5 W

CHEMICAL COMPATIBILITY

Gas compatibilityDry, oil-free gas, air, any non corrosive or non explosive gas
Liquid compatibilityAqueous solvent, oil, organic solent, biological sample

OxyGEN

Control in real-time, protocol automation, data record and export
ver. 2.2.0.0 or more recent

See the offer


Software Development Kit

Custom software application
ver. 22.2.0.0 or more recent

See the offer

Migrating cells in gradient

Migrating cells in dynamic chemical gradients generated by a microfluidic chamber (cells, gray; chemoattractant with fluorescein,green). Video courtesy of Pr Satoshi Sawai ( University of Tokyo, Japan).

Microfluidic cell sorting

With the Fluigent Microfluidic Flow Control System (MFCS-4C) one can sort cells by size, shape and deformability as shown in this publication in the journal Lab-on-a-Chip and explained in the next video.

Separation of parasites from human blood

See an example of applications using the MFCS series: « Separation of parasites from human blood using deterministic lateral displacement, S. H. Holm, J. P. Beech, M. P. Barrett and J. O. Tegenfeldt, Lab Chip, vol.11, 2011

Microfluidic cell perfusion

The MFCSTM series and Flow EZTM with Fluigent valves can be used for automated cell perfusion as in the next video.

Expertise & resources

  • Microfluidics case studies CNRS/UTC: study of a liver-on-a-chip model Read more
  • Expert Reviews: Basics of Microfluidics Choosing the Right Microfluidic Pressure Range Read more
  • Fluigent product icons & images Fluigent product icons & images Read more
  • Interviews & Testimonials Testimonials MFCS Series Read more
  • Microfluidics case studies Success story of SEED Biosciences : Single-cell injection and impedance analysis Read more
  • Microfluidics case studies University of Cambridge: Giant unilamellar vesicle production and testing Read more
  • Microfluidics case studies The Micro/Nano Bioelectronics and Biosensors (MBIOS) from Tianjin University Read more
  • Microfluidic Application Notes Microbiome culture in droplet using dsurf surfactant Read more
  • Microfluidic Application Notes Droplet and particle manipulation using electrophoretic flow control Read more
  • Expert Reviews: Basics of Microfluidics High Throughput Single Cell Analysis Read more
  • Microfluidic Application Notes Cartilage-on-a-chip, an example of complex mechanical stimulation using Fluigent’s technology     Read more
  • Technical datasheets MFCS™-EX Datasheet Download
  • Technical datasheets MFCS™-EZ Datasheet Download
  • User manuals MFCS™ series User Manual Download
  • Expert Reviews: Basics of Microfluidics Instrument Stability in Microfluidics  Read more
  • Expert Reviews: Basics of Microfluidics Flow control for droplet generation using syringe pumps and pressure-based flow controllers  Read more
  • Expert Reviews: Basics of Microfluidics Extended capabilities of pressure driven flow for microfluidics applications Read more
  • Expert Reviews: Basics of Microfluidics Microfluidic instrument responsiveness Read more
  • Expert Reviews: Basics of Microfluidics Microfluidic Resistance Read more

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Accessories

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  • Airtight metal tube caps for microfluidics

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  • Microfluidic Low Pressure Generator

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Kits

  • MFCS series low pressure tubing & fitting kit

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  • MFCS series high pressure kit

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