Integrate a pressure/vacuum source
Microfluidic Flow Control System
- Customize your own
The MFCS™ is a pressure based microfluidic flow controller. Either 4 or 8 channels are available with different pressure ranges for microfluidic experiments. By using the FASTAB™ microfluidic patented technology, the MFCS™ generates a constant pressure-driven flow rate that allows for reliable and repeatable experiments.
Up to 8 channels with various ranges
Patented & Field-proven technology
Flat & Light design for benchtop use
Easy to set up & use
The MFCS™ can be controlled by Fluigent software to automate your protocols. It can easily be connected to other microfluidic devices such as FLOW UNIT sensors to allow for flow-rate control.
Each channel can be controlled independently and deliver a specific amount of pressure or vacuum to handle fluids. Range available from -800 mbar for vacuum aspiration and up to 7 bar for pressure.
Get superior results rapidly
Reach your pressure targets rapidly and get your experiment started instantaneously. The field-proven technology ensures to obtain quickly reliable and superior results for your experiments.
Reliable & Reproducible results
The FASTAB™ microfluidic patented technology used by MFCS™ series avoids cross contamination as there is no direct contact between the instrument and the reagents. The pulseless and precise control enabled by our pressure-driven technology is critical for repeatable results in many applications.
Adaptability & Integration
The MFCS™ system can provide negative or positive pressures as needed by using up to four or eight independently controllable channels. In addition, a microfluidic pressure pump can easily be integrated into a setup with the Software Development Kit (SDK).
The conception of a MFCS™ controller depends on your needs. You can choose the number of channels of the device (4 or 8), each channel range from -800 mbar to 7 bar, and you even have the possibility to integrate a pressure or vacuum source inside the instrument. Customize your own controller to answer your control needs.
The MFCS™ series product range is the first generation of microfluidic systems. Along with the MCFS™-EZ or MCFS™-EX, a Manifold can be added to redirect the pressure to multiple fluid reservoirs.
The flow generated can be measured or controlled with FLOW UNITs and the Flowboard. The MFCS™-EX provides up to 8 negative or positive pressure channels to pressurize multiple fluid reservoirs. It can have an integrated pressure/vacuum source or be coupled with the FLPG+, an external pressure source, for those who don’t have access to a laboratory bench mounted gas source. This system can be integrated, automated or control in real time by using Fluigent Software Solutions.
The technology used in this pressure pump avoids cross contamination because liquids only contact air. Improved reliability and reproducibility of of results is possible due to the pulseless flow. The use of pressure to handle fluids also provides a quick response time allowing for precise operations such as stop flow and accurate pressure/flow rate steps. The MFCS™ series products are well adapted to the manipulation of fluid volumes in the low to sub microliter per minute range.
|Output pressure stability||Highly monodispersed droplet size – No oscillation|
|System settling time||No transitory regime – Reagent saving – Stop-flows|
|Volumes||Wide range of volume can be controlled – No compromise between volume and stability|
|Flexibility||Any mix or pressure ranges are available – Highly customizable|
|Channel part number (MFCS™-EZ)||Channel part number (MFCS™-EX)||Pressure/Vacuum range||Required supply|
|EZ-00345001||EX-00345001||0 to 345 mbar (0 to 5,00 psi)||1100 mbar (15,95 psi)|
|EZ-01000001||EX-01000001||0 to 1000 mbar (0 to 14,50 psi)||1100 mbar (15,95 psi)|
|EZ-01000002||EX-01000002||0 to 2000 mbar (0 to 29,01 psi)||2100 mbar (30,46 psi)|
|EZ-07000001||EX-07000001||0 to 7000 mbar (0 to 101,5 psi)||7100 mbar (103,0 psi)|
|EZ-80025001||EX-80025001||0 to -25 mbar (0 to -0,36 psi)||-800 mbar (-11,6 psi)|
|EZ-80069001||EX-80069001||0 to -69 mbar (0 to -1,0 psi)||-800 mbar (-11,6 psi)|
|EZ-80345001||EX-80345001||0 to -345 mbar (0 to -5,00 psi)||-800 mbar (-11,6 psi)|
|EZ-80800001||EX-80800001||0 to -800 mbar (0 to -11,6 psi)||-800 mbar (-11,6 psi)|
|Dimensions||MFCS™-EZ: 160 x 230 x 63 mm|
|Weight||MFCS™-EZ: 2.0 kg (4.4 lbs)|
|Output connectors||Female luer lock (-800 to 2000 mbar) – 4mm OD tube (7 bar)|
|Power consumption||1.5 W|
|Gas compatibility||Dry, oil-free gas, air, any non corrosive or non explosive gas|
|Liquid compatibility||Aqueous solvent, oil, organic solent, biological sample|
|Control in real-time, protocol automation, data record and export|
|ver. 18.104.22.168 or more recent|
Software Development Kit
|Custom software application|
|ver. 22.214.171.124 or more recent|
Migrating cells in gradient
Migrating cells in dynamic chemical gradients generated by a microfluidic chamber (cells, gray; chemoattractant with fluorescein,green). Video courtesy of Pr Satoshi Sawai ( University of Tokyo, Japan).
Microfluidic cell sorting
With the Fluigent Microfluidic Flow Control System (MFCS-4C) one can sort cells by size, shape and deformability as shown in this publication in the journal Lab-on-a-Chip and explained in the next video.
Separation of parasites from human blood
See an example of applications using the MFCS series: « Separation of parasites from human blood using deterministic lateral displacement, S. H. Holm, J. P. Beech, M. P. Barrett and J. O. Tegenfeldt, Lab Chip, vol.11, 2011
Microfluidic cell perfusion
The MFCSTM series and Flow EZTM with Fluigent valves can be used for automated cell perfusion as in the next video.
Expertise & resources
Microfluidics case studies CNRS/UTC: study of a liver-on-a-chip model Read more
Fluigent product icons & images Fluigent product icons & images Read more
Interviews & Testimonials Testimonials MFCS Series Read more
Microfluidics case studies Success story of SEED Biosciences : Single-cell injection and impedance analysis Read more
Microfluidics case studies University of Cambridge: Giant unilamellar vesicle production and testing Read more
Microfluidics case studies The Micro/Nano Bioelectronics and Biosensors (MBIOS) from Tianjin University Read more
Microfluidic Application Notes Microbiome culture in droplet using dsurf surfactant Read more
Microfluidic Application Notes Droplet and particle manipulation using electrophoretic flow control Read more
Expert Reviews: Basics of Microfluidics High Throughput Single Cell Analysis Read more
Microfluidic Application Notes Cartilage on chip using Fluigent MFCS pressure controller Read more
Technical datasheets MFCS™-EX Datasheet Download
Technical datasheets MFCS™-EZ Datasheet Download
User manuals MFCS™ series User Manual Download
Expert Reviews: Basics of Microfluidics Microfluidic Instrument Stability Read more
Expert Reviews: Basics of Microfluidics Droplet generation using syringe pumps and pressure-based flow controllers Read more
Expert Reviews: Basics of Microfluidics Extended capabilities of pressure driven flow for microfluidics applications Read more
Expert Reviews: Basics of Microfluidics Microfluidic instrument responsiveness Read more