Double emulsion for the generation of microcapsules - a Review​

Controlled double emulsification process for encapsulation

Using droplet-based microfluidics as a method for generating microcapsules is of growing interest in the scientific community, as it offers great potential in delivering active pharmaceuticals ingredients (APIs). The molecule can be encapsulated in the core of the droplets, surrounded by a protective shell that enables the transport of the drug to specific locations of the body, while eliminating, unwanted secondary effects and collateral damages. 

While conventional bulk methods for the generation of microcapsules are limited by droplet polydispersity and high reagent loss, microfluidics offers a way to produce highly-monodisperse double emulsions with a higher encapsulation efficiency. Here, we present different ways to generate double emulsions for microcapsule production using the complex emulsion platform, developed by Secoya and equipped with our pressure-based flow control technology. 

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