Electrical impedance spectroscopy package

A complete system to start EIS experiments

Electrical impedance spectroscopy (EIS) is a technique that guarantees fast throughput and label-free sensing so that it can be used to characterize electrical properties, size, or morphology of cells in microfluidic devices. Fluigent and Zurich Instruments drew on their expertise to propose a complete solution for EIS in microfluidics.

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Main benefits

Save time
Label-free analysis
Flexible
Wide range of analysis tools
Cost-effective
Small sample volumes

Features

Microfluidic EIS

Good integration with other analysis methods (e.g. optical detection), the EIS instruments allow for simultaneous multi-frequency measurement.

Complete system

With this package, you have all the fluidic components necessary to start EIS experiments.

Engineered solution

We built the package with the right pressure controllers, microfluidic chips.

Customization possible

We can adapt the package to fulfill your needs.

Related applications

Working principle

The microfluidic EIS technique involves monitoring the change in the frequency-dependent dielectric properties of the channel as the cell passes through it. The measurement requires both high sensitivity and fast response.

As the analyte enters and exits the differential electrode pairs in a microfluidic chip, a peak and a trough in current are observed. With a differential input, the signal from the surrounding fluid is suppressed, meaning each cytometry event can be resolved with reduced noise.

The importance of pressure-based flow control

Control flow rate with the benefits of responsive, pulse free flow

Pulse-free flow is critical for generating high quality and repeatable results. The Flow EZ™ integrates the all-new DFC (Direct Flow Control) algorithm which allows the user to set a flow rate directly on the instrument display. The applied pressure will automatically adjust to maintain the flow rate.

A response time ten times faster compared to mechanical solutions

With the use of pressure instead of mechanical action, the Flow EZTM gets responsiveness ten times faster than syringe pumps. A low response time allows one to quickly execute operations such as stop flow and pressure/flow rate steps.

Specifications

LineUp Flow EZ pressure controller (2000 mbar) x2

LineUp LINK Module (software control) x1

FLOW UNIT M (x1) and L (x1)

Electrical impedance spectroscopy chip and holder (contact us)

HF2LI from Zurich Instruments

HF2TA from Zurich Instruments

Kit including all necessary tubing & fittings

OxyGEN

Control in real-time, protocol automation, data record and export

ver. 1.0.0.0 or more recent

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Software Development Kit

Custom software application

ver. 21.0.0.0 or more recent

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Electrical impedance spectroscopy package