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10-way bidirectional valve to perform sequential injection/distribution

  • Easy to setup and use
  • Compact
  • Adaptable
  • Chemical and biological compatibility

A bidirectional 11-port / 10-way valve for injection or selection of up to 10 different fluids controlled by our software.


M-SWITCH biology technology

The M-SWITCH™ is an 11-port / 10-way rotary valve: peripheral ports (numbered from 1 to 10) can be connected to a central channel (C).

The M-SWITCH™ is electrically actuated by a motor that drives a rotor – where the fluidic path is engraved – against a stator – hosting the fluidic ports.

It also can be used with our manifold to improve your experiments and simplify your setups.



The flow is bidirectional in the M-SWITCH™, meaning that the device can be used as a selector and a distributor for either multiplexing or demultiplexing purposes. It is also very important to control the path of the sample and reagents inside the microfluidic system, from the right inlet into the right channels and to the right outlet (to a collector reservoir, another chip or a waste reservoir). To achieve that, we often have to sequentially open and close the different inlets and outlets of the microfluidic device, so that the intended flow path in the chip can become the least resistive path, where the fluids will naturally flow. “On-off” and 2-way switch valves such as the ESS™ 2-SWITCH™ are useful for this purpose.


The ESS™ M-SWITCH™ selection valve enables you to connect all buffers to the same device and to have only one tube going to the chip. By selecting the position of the M-SWITCH™ one can choose which of the connected buffers will be directed to the device by the Microfluidic Flow Control System (MFCS™-EZ).

The diagram shows how to use an M-SWITCH™ to perform a sequential injection of up to 10 different reagents inside an on-chip reactor. The reagent flow is controlled by Fluigent (MFCS™-EZ + Flow Rate Platform) flow control devices, and injected into the chip as selected by the M-SWITCH™. In the diagram, Reagent #2 is injected. This type of fluidic path can be very useful for sample preparation, cell analysis, fluorescent labelling, drug screening, and more.

NB: If the M-SWITCH™ is not used with our MFCS™-EZ pressure controller, the maximum pressure that can be applied is 7 bar.

microfluidic valve selection
cell buffer selection switch


• Chemical and biological compatibility (wetted materials: RPC7)
• Low internal volume (11.6µL)
• Automated control
• No dead volume
• Integrated fittings
• Port-to-port switching time: 280ms


• Continuously monitor experimental status
• Save time with automation capabilities
• Simplify chip design
• Save bench space
• Maintain sample integrity
• Reduce reagent consumption
• Communicate with external devices


• Maximum applied pressure: 7bar
• Size: 7x9x14.5cm3
• Weight: 400g

• Power supply: RJ45 to the SWITCHBOARD
• P/N = MSW002 (Product Number)


The ESS™ Control software allows you to control each ESS™ products including the M-SWITCH™.

We have also developed many features to simplify routine experiments

  • Ability to record and log the positions of all devices during the experiment.

  • Save a set of parameters as a configuration/method.

  • Modular display of your devices: the main window can be contracted and expanded.

  • Every M-SWITCH™ control can be undocked and displayed in an individual and repositionable compact window.

  • Customize the interface, such to include switch names and fluidic ports for ease of identification.

automated switch control software
icon questions


  1. Stop your experiment and remove the liquid that spilled out of the valve.
  2. Check the following points :
    • Use 1/16’’OD (Outer Diameter) tubing only
    • Use plugs on the non used ports
    • Mark tubing at 24mm from the end. This length of tubing should be inside of the M-SWITCH™. It will be an indicator to ensure that the tubing is fully seated
    • Use same tubing material (PEEK/FEP/ etc…) on all the ports of the M-SWITCH™
    • Well tighten the spanner. To check the tightness of your connection, you may pull gently on the tubing & plugs

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To learn how to connect the M-Switch™ on the Switchboard, go to the ESS™ section.

Concerning the tubing connection:

M-Switch faq 1
M-Switch faq 2
M-Switch faq 3
M-Switch faq 4
M-Switch faq 5
  • Cut the 1/16’’ OD tubing to the desired length, leaving a square-cut face. For connecting a plug, take one of the plugs provided by Fluigent.
  • Mark each piece of tubing or plug 24mm from the end (it will be an indicator to ensure that the tubing is fully seated).
  • Loosen the Spanner adequately to release the ferrules of the integrated fittings.
  • Insert the piece of tubing or plug in one port and push it all the way to the bottom of the port. The mark made at step 2 should be approximately flush with the top of the ram when tubing is fully seated.
  • Once tubing or plugs have been inserted in all ports, tighten the spanner to clench the fittings around tubing and plugs and have a tight connection. To check the tightness of your connection, you may pull gently on the tubing and plugs: they must stay fitted in the integrated fittings.
  • Warning:
  • The M-SWITCH™ device can only be connected with 1/16’’ OD tubing.
  • All ports need to be connected: Use plugs on the non-used ports.
  • Use the same tubing material (PEEK/FEP) on all the ports to have a well tighten of the spanner.

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You can clean the M-Switch™ in the same way than the Flow Unit.

Besides, Fluigent strongly advises you to use filtered solutions. Wetted materials are custom polymer RPC7 only.

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The M-SWITCH™ can only be connected with 1/16’’ OD tubing. There is a wide variety of materials and internal diameters available with 1/16’’ OD tubing to suit your application. However, if you have constraints on your fluidic setup that force you to use tubing of other external diameters than 1/16’’, a wide range of adaptors and unions are available from the fittings suppliers, to make a junction between your specific tubing and the M-SWITCH™ tubing.

Warning: Please note that sleeves cannot be used directly in the M-SWITCH™ fluidic ports (risks of trapping the smaller tubing and possible non-tight connection).

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