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March 31, 2023
Development of an in-vitro eye model with the Flow EZ
Development on an in-vitro model to estimate mass transfer from the anterior cavity
📢 A new research paper by Tianyang Liu and colleagues from the 𝗢𝗽𝘁𝗰𝗲𝘂𝘁𝗶𝗰𝘀 𝗟𝘁𝗱, UCL School of Pharmacy and the National Institute for Health Research, London, UK, describes a 𝗻𝗲𝘄 𝗶𝗻-𝘃𝗶𝘁𝗿𝗼 𝗲𝘆𝗲 𝗺𝗼𝗱𝗲𝗹 to estimate mass transfer through the iris/lens barrier in the case of drug intracameral injection.
👉 https://www.frontiersin.org/articles/10.3389/fddev.2022.1025029/full
The article relies on the 𝗶𝗺𝗶𝘁𝗮𝘁𝗶𝗼𝗻 𝗼𝗳 𝗶𝗻-𝘃𝗶𝘃𝗼 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 by reproducing several eye movements and perfusing the system at physiological flow-rates using 𝗙𝗹𝘂𝗶𝗴𝗲𝗻𝘁’𝘀 𝗙𝗹𝗼𝘄 𝗘𝗭, 𝗙𝗟𝗣𝗚 𝗣𝗹𝘂𝘀, 𝗟𝗜𝗡𝗞, 𝗔𝗗𝗔𝗣𝗧, 𝗙𝗹𝗼𝘄 𝗨𝗻𝗶𝘁 𝗦 𝗮𝗻𝗱 𝘀𝗼𝗳𝘁𝘄𝗮𝗿𝗲.
#EyeOnChip #PressureControl #microfluidics
