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Development of an in-vitro eye model with the Flow EZ

March 31, 2023
in vitro eye model

Development on an in-vitro model to estimate mass transfer from the anterior cavity

๐Ÿ“ข A new research paper by Tianyang Liu and colleagues from the ๐—ข๐—ฝ๐˜๐—ฐ๐—ฒ๐˜‚๐˜๐—ถ๐—ฐ๐˜€ ๐—Ÿ๐˜๐—ฑ, UCL School of Pharmacy and the National Institute for Health Research, London, UK, describes a ๐—ป๐—ฒ๐˜„ ๐—ถ๐—ป-๐˜ƒ๐—ถ๐˜๐—ฟ๐—ผ ๐—ฒ๐˜†๐—ฒ ๐—บ๐—ผ๐—ฑ๐—ฒ๐—น to estimate mass transfer through the iris/lens barrier in the case of drug intracameral injection.

The article relies on the ๐—ถ๐—บ๐—ถ๐˜๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ผ๐—ณ ๐—ถ๐—ป-๐˜ƒ๐—ถ๐˜ƒ๐—ผ ๐—ฐ๐—ผ๐—ป๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป๐˜€ by reproducing several eye movements and perfusing the system at physiological flow-rates using ๐—™๐—น๐˜‚๐—ถ๐—ด๐—ฒ๐—ป๐˜โ€™๐˜€ ๐—™๐—น๐—ผ๐˜„ ๐—˜๐—ญ, ๐—™๐—Ÿ๐—ฃ๐—š ๐—ฃ๐—น๐˜‚๐˜€, ๐—Ÿ๐—œ๐—ก๐—ž, ๐—”๐——๐—”๐—ฃ๐—ง, ๐—™๐—น๐—ผ๐˜„ ๐—จ๐—ป๐—ถ๐˜ ๐—ฆ ๐—ฎ๐—ป๐—ฑ ๐˜€๐—ผ๐—ณ๐˜๐˜„๐—ฎ๐—ฟ๐—ฒ.

#EyeOnChip #PressureControl #microfluidics

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