Microfluidic OEM Flow Sensor

[IFSXX]

New release

FS+ series

Our microfluidic OEM flow sensor FS series is dedicated to flow rate control and monitoring. When combined with Fluigent pressure controllers, it permits pressure-based flow control. It enables precise and accurate measurements of dynamic liquid flow rates from 0 – 1.5 µL/min and up to 40 mL/min bi-directionally.

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Bidirectional flow sensors for OEM applications

Main benefits

Short response time
Pressure-based direct flow rate control
High stability
High reliability & long-term stability
Reliable
Industry-proven technology
Intuitive
Easy-to-use systems

Features of our microfluidic OEM flow sensor

High accuracy for various flow rate ranges

Highly precise flow measurement with an accuracy of less than 5% error on the measured value. The different Flow Sensor models offer an extensive choice of flow-rate ranges to best match your needs over the range of 7nL/min to 40 mL/min.

Plug & Play

Using Fluigent electronics and algorithms, the sensors are directly recognized by Fluigent systems and SDK/software for starting experiments right away.

Compact and fast integration

The sensors were developed to be cost-effective and easily integrated into any system.

Air bubble detection*

In addition to liquid monitoring, it is possible to detect bubbles using the microfluidic OEM flow sensor during an experiment.

*Bubble detection is only available for the FS+ series

Related applications

Benefits of the FS Series and FS Series + microfluidic OEM flow sensor

Fluigent provides highly stable and responsive real-time flow control

By directly connecting a microfluidic OEM flow sensor to Fluigent pressure controllers, it is possible to monitor or control the flow rate in real time. The algorithm includes a continuous optimization of the parameters, allowing it to adapt to the interactions between fluidic channels in complex situations.

Fluigent’s powerful pressure regulation algorithm is based on physical equations and self-learning routines that offer several benefits:

No overshoot/undershoot, allowing for a responsive, accurate, and stable flow rate

Adapts to any reservoir size

Compatible with a wide pressure or vacuum range (up to 7,000 mbar, -800 mbar vacuum, standalone pressure/vacuum regulation capability)

Flow rate is sometimes vital for you application

Flow rate may need to be tightly controlled for a number of applications. In droplet microfluidics, it is useful to correlate the droplet size with the droplet frequency (generation rate). For dynamic organ-on-chip applications, the flow rate is needed to evaluate the shear stress imposed on cells. It is also an important feature for applications that require dispensing a specific volume of liquid, such as for cell imaging applications in which various reagents are delivered. Fluigent microfluidic OEM flow sensor is suitable for all types of aqueous liquids, such as distilled water, media, PBS, etc.

It is useful for many biological applications, including:

Next-generation sequencing (NGS) applications using microfluidic Digital PCR to quantify ctDNA in liquid biopsies for oncology, to detect low-level genetic variants in infectious diseases

Microscopy for cell biology research, DNA-PAINT imaging, genomics research, live cell imaging

Drug discovery using microphysiological systems such as 3D-(co)-cultures, organoids, organ-on-chip models

Molecular analysis including microfluidic modulation spectroscopy or mass photometry

Mid- and high-flow applications (7uL/min – 40 mL/min): FS + series

For applications that require flow rates ranging from 7 µL/min to 40 mL/min, we recommend our latest microfluidic OEM flow sensor series. It consists of a high-precision sensor and electronics integrated into a compact casing. Standard M3 sized screws can be used for fixing the device. Using these flow sensors, one can also monitor liquid temperature and detect air bubbles that pass through the sensor.

Two references are available: L+ and M+

FS series L+

H₂O full-scale flow rate: 0 – ± 40 mL/min*

Accuracy: ±5 % of measured value if flow rate > 1 mL/min,

50 µL/min if flow rate < 1 mL/min

*Additional specifications available on the specification table and on the datasheet

FS series M+

H₂O full-scale flow rate: 0 – ± 2 mL/min*

Accuracy: ±5 % of measured value if flow rate > 10 µL/min,

0.5 µL/min if flow rate < 10 µL/min

*Additional specifications available on the specification table and on the datasheet

Low flow applications (< 7 uL/min): FS series

For applications that require flow rates lower than 10 µL/min, we recommend our original flow sensor series.

Two references are available: XS and S

Specifications

Sensor performance

	FS series	FS series	FS+ series	FS+ series
Sensor model	XS	S	M+	L+
Calibrated media	Water	Water IPA	Water IPA	Water IPA
Range	0±1.5µL/min	0±7µL/min 0±70µL/min	0±2mL/min	0±40mL/min
Accuracy (m.v.= measured value) also applies to negative values	Water 10% m.v. above 75 nL/min 7.5 nL/min below 75 nL/min	Water 5% m.v. above 0.42 µL/min 21 nL/min below 0.42 µL/min IPA 20% m.v. above 4.2 µL/min 210 nL/min below 4.2 µL/min	Water 5% m.v. above 2.4 µL/min 0.12 µL/min below 2.4 µL/min IPA 20% m.v. above 25 µL/min 5 µL/min below 25 µL/min	Water 5% m.v. above 0.04 mL/min 1.5 µL/min below 0.04 mL/min IPA 20% m.v. above 0.5 mL/min 100 µL/min below 0.5 mL/min
Lowest detectable flow increment	3.7 nL/min	10 nL/min

Mechanical specifications

	FS series	FS series	FS+ series	FS+ series
Sensor model	XS	S	M+	L+
Sensor diameter	25 µm	150 µm	430 µm	1.0 mm
Maximum pressure	200 bar	200 bar	100 bar	15 bar
Wetted materials	PEEK & Quartz Glass	PEEK & Quartz Glass	PPS, stainless steel 316L Fittings: PEEK/ ETFE	PPS, stainless steel 316L Fittings: PEEK/ ETFE
Dimensions	53x22x9mm	53x22x9mm	65x36x25mm	65x36x25mm
Total mass	10g	10g	50g	50g
Length of the electrical cable	1.5m	1.5m	1.5m	1.5m
Inner volume	1µL	1.5µL	~ 28µL	~ 28µL
Sensor inner diameter	25µL	150µL	400µL	400µL
Fluid connector ports	UNF 6-40 for 1/32” OD tubing	UNF 6-40 for 1/32” OD tubing	UNF 1⁄4′′-28 flat bottom for 1/16” OD tubing	UNF 1⁄4′′-28 flat bottom for 1/16” OD tubing

OxyGEN

Control in real-time, protocol automation, data record and export

ver. 1.0.0.0 or more recent

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Software Development Kit

Custom software application

ver. 21.0.0.0 or more recent