Ready to use system
Microfluidic Recirculation PackO-RECIR-PCK
A ready-to-use pack for unidirectional and stable fluid recirculation
Cell culture is considered the foundation of many areas of cell biology research, including studies of cellular metabolism, gene expression, and signal transduction. Recently, a new field called organ-on-a-chip (OOAC) has begun to emerge, seeking to mimic the structure and function of organs using microfluidic cell culture systems. The goal of OOAC technology is to create miniature versions of human organs that can be used to study diseases, drug interactions, and toxicology in a more realistic and precise way than traditional cell culture or animal models. This allows for the production of in-vitro models reproducing physiologically relevant features observed in-vivo.
In order to maintain a cell culture or an OOAC system alive and functional over a long period of time, and due to the low volume contained in a microfluidic channel, recirculation is mandatory. It allows for constant provision of nutrients to the cells and application of a constant shear-stress, which is of primary importance for organ-on-chip technologies.
Our Microfluidic Recirculation Pack offers the ability to provide cells with a continuous flow, thereby controlling the transport of nutrients and the active mechanical constraints applied in the channel.
- Cost effective
Small sample volumes
- Time saving
Automated circulation and switching
Features of the pack
Our recirculation pack includes all the necessary components for your experiment.
Generate complex flow patterns
Control flow rate or pressure for applications with constant shear stress, such as vascular perfusion.
Dedicated protocols for long-lasting experiments
Build customized, time-based protocols to save time and reduce variability.
With OxyGEN’s automated Recirculation protocol, experiments can be prolonged to last up to 60 hours or more with a fixed amount of fluid.
Drastically reduce the volume of your experiments and the amount of fluid needed with recirculation.
Shear stress control
Our recirculation pack’s precision and short switching time allow for control of shear stress inside the chip throughout the experiment.
Key products in the Microfluidic Recirculation Pack
Our Microfluidic Recirculation Pack contains :
|LineUp Flow EZ pressure controller (345 mbar) (x2)|
|LineUp LINK Module (software control) (x1)|
|FLOW UNIT M (x1)|
|SWITCH EZ (x1)|
|P-CAP series 15 mL (x2)|
FLUID HANDLING SYSTEM
|2*15 mL Pcap with 15 mL Falcon tube||P-CAP15-HP|
|2*Fluidic T junction||CTQ-TFLU|
|1*Flow unit M||FLU-M-D|
|1*Tubing and connection Kit P-CAP 15mL |
FEP tubing with an ID of 500 microns
|2*Tubing and connection Kit 2-SWITCH||CTQ-KIT-2SW2|
|1*Tubing and connection Kit Flow UNIT M||CTQ-KIT-LQ|
|Control in real-time, protocol automation, data record and export|
|ver. 18.104.22.168 or more recent|
Software Development Kit
|Custom software application|
|ver. 22.214.171.124 or more recent|