< 2% CV
Nanoparticle Production Pack
[O-MIX-LIPO-PCK] or [O-MIX-PLGANP-PCK]Complete system for producing nanoparticles in a reproducible manner
The Fluigent Nanoparticles Production Pack is a robust and complete system for precise and long-term production of nanoparticles with high flexibility in terms of particle size range. The pack includes Fluigent’s LineUP microfluidic pumps and Secoya's RayDrop device- a breakthrough in technology for high-quality particle production.
Main benefits
High precision- Flexible
Adjustable particle size
- Robust
Continuous production
Features of the Nanoparticle Production Pack
Complete System
With this package, users have all the components necessary to start generating nanoparticles with high monodispersity and high stability.
Dedicated Protocol
A protocol is available to assist users in setting up and starting your experiments
Engineered Solution
We built the package with the right pressure controllers, microfluidic chips, and valves to make sure you have the highest flexibility in terms of particle size and generation rate
Customization Possible
We can adapt the package to fulfill your needs (particle size, generation rate)
Related applications
Main Products of the Nanoparticle Production Pack
With the components of the nanoparticle production pack, users can produce nanoparticles with high monodispersity. This pack controls the size of the nanoparticles, increasing the range of applications in which they can be used.
Specifications
| LineUp Flow EZ pressure controller (2000 mbar) x2 |
| LineUp LINK Module (software control) x1 |
| FLOW UNIT M (x1) and L (x1) |
| P-CAP series 15 mL (x3) |
| LineUp Switch EZ (x1) |
| 2-SWITCH x2 |
| Raydrop Single Emulsions x1 |
| SWITCH EZ x1 |
Liposome Nanoparticles Production
| Inner phase | Absolute ethanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL |
| Outer phase | Phosphate-buffered saline (PBS) (pH 7.2) |
| Particle size range | 30 nm to 150 nm |
| Polydispersity | From 7% to 15% |
PLGA Nanoparticles Production
| Inner phase | Acetone + Poly(lactic-co-glycolic acid) (PLGA) Resomer 756 1%hanol + Lipids 10 mg/mL + Dimethyldioctadecylammonium (DDAB) 2.5 mg/mL |
| Outer phase | Deionized water + Polyvinyl alcohol (PLGA) Mw 90000 – 10000 80 % hydrolyzed |
| Particle size range | 100 to 250 nm |
| Polydispersity | From 5% to 15% |
Flow Control
| Pumps | Fluigent Flow EZ (2000mbar) |
| Flow Sensors | Fluigent FLOW UNIT (M & L) |
| Automated valves | Fluigent 2-SWITCH |
Imaging (optional)
| Microscope | Fluigent Digital high-speed microscope |
OxyGEN
| Control in real-time, protocol automation, data record and export |
| ver. 1.0.0.0 or more recent |
Software Development Kit
| Custom software application |
| ver. 21.0.0.0 or more recent |
Imaging
| Pixelink Capture Software |
| Extrusion method | Fluigent microfluidic method | |
| Particle size distribution | up to 50% | ~ 2% |
| Reproducibility | low | High |
| Particle size control | no | Precise |
| Continuous (in line) production | no | yes |