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We use human intestinal biopsies to study drug absorption and toxicity inside an in-house engineered microfluidic system. For this we are using Fluigent pumping system to create a controlled flow inside the microfluidic chip while having simple and robust interface for medium throughput applications.

Evita van de Steeg, PhD
Hossein Eslami Amirabadi, PhD

TNO ZEIST /
ZEIST, THE NETHERLANDS / DECEMBER, 2019

The Experimental Soft Matter Physics group uses solutions provided by Fluigent for controlling fluid flow in their research on microfluidic production of liquid crystal shells, and electrospinning as well as microfluidic wet spinning of liquid crystal core-functionalized polymer fibers. Moreover, the low-pressure units are used in a microfluidic device for measuring interfacial tension that was developed in the group.

Prof. Dr. Jan LAGERWALL

UNIVERSITÉ DU LUXEMBOURG / LUXEMBOURG / DECEMBER, 2019

With my team, we have been using Fluigent systems for about 10 years for a great variety of projects, ranging from single cell trapping and manipulation to the application of multi-modal mechanical stimulation in organ-on-a-chip platforms. Fluigent systems are in general extremely accurate, they are user-friendly and their very fast response time is ideal for some of our applications requiring quick switching between different pressures.

Séverine Le Gac

UNIVERSITY OF TWENTE /
ENSCHEDE, THE NETHERLANDS / JULY, 2019

The Microfluidics Laboratory of the ESPCI has used the Fluigent equipments for almost 10 years. Pressure-driven fluid handling brought a lot of flexibility and robustness in our daily experiments. The MFCS™-EZ is a strong and reliable device, able to adapt to all types of microfluidic experiment. The range complete by adding flow sensors able to transform the MFCS™-EZ into a full flow-rate piloting system with the FRP. Our laboratory trust Fluigent products, engineers, software developers as well as the entire team that makes every day a great job.

Fabrice Monti

MMN LABORATORY, IPGG / PARIS, FRANCE / FEBRUARY 4, 2015

As a team working in Droplet based microfluidic we’ve been using Syringe pumps. Involved in a new research program, we decided to switch our former equipment for a Fluigent flow rate control solution Microfluidic flow control system (MFCS™-EZ) + (FLOWELL, old Flow-Rate Platform, with Flow Rate Control Module). We observed a real improvement as this system based on the control of pressure is more responsive and stable. In our specific application microfluidic systems usually need some time to stabilize while the Fluigent solution allows a quick start or stop. It is also very flexible as it allows stopping and restarting the droplet manipulation, the change of reservoir or sample during an experiment, with almost no impact on the experiment. Besides, the pressure regulation enables to limit the maximum pressure applied to the chip and allow us to preserve the integrity of our chip especially those with long channels.

Raphael Calbrix

PLATE-FORME DE CHIMIE BIOLOGIQUE INTÉGRATIVE DE STRASBOURG (PCBIS) / ECOLE SUPÉRIEURE DE BIOTECHNOLOGIE STRASBOURG (ESBS) FRANCE

We have found the Fluigent equipment to be very helpful to our microfluidic research on various fluid mechanics and transport problems. For example, in order to investigate diffusion of nano particles inside a microfluidic channel, we originally tried to generate a concentration gradient along a closed channel by constantly flowing solutes across one open end. We recognized the need to generate a steady flow that minimized pressure fluctuation or other perturbations, which we found inevitable with motor-driven pumps. With aid of the Fluigent Microfluidic flow control system (MFCS™-EZ) and Flow-Rate Platform (FRP), we were able to achieve a fluctuation-free, perfectly steady flow, which allowed us to generate a constant concentration along the targeted area. The new research results we have obtained were made possible by the high quality and ease of use of the Fluigent equipment.

Howard Stone and Sangwoo Shin

DEPARTMENT OF MECHANICAL AND AEROSPACE ENGINEERING / PRINCETON UNIVERSITY, USA

We use Fluigent precision pumps to control flow in a Cancer-on-Chip set up with top and bottom flow. The biological material is thin slices (0.3 mm) derived from tumors (patient derived xenograft or directly from surgical resection in the hospital). The tumor slices are maintained under constant flow for one to two weeks without loss of tissue integrity, viability or proliferation.

Dik van Gent, Associate Professor

DEPARTMENT OF MOLECULAR GENETICS
ERASMUS UNIVERSITY MEDICAL CENTER
ROTTERDAM, THE NETHERLANDS / DECEMBER 2019

Fluigent systems grant at the same time high-precision real-time control and long-term stability of flow, which are both crucial for my applications. Fluigent team is always available to help designing and optimizing flow control strategies and keen to develop their systems to meet the needs of the state-of-the-art microfluidic applications.

Eleonora Secchi

ETH ZÜRICH, INSTITUTE OF ENVIRONMENTAL ENGINEERING
ZÜRICH, SWITZERLAND / DECEMBER 2019

We have bought Fluigent flow control solution (MFCS™ + FLOWELL, old Flow-Rate Platform, with Flow Rate Control Module) to replace our usual high precision syringe pumps to generate monodisperse microfluidic droplets. Fluigent solution provides a very efficient and reliable flow rate control as well as a significantly higher stability at low flow rates in comparison with syringe pump-based systems. The whole set-up including both hardware and software is very intuitive and easy to work with.

Michael Ryckelynck Associate Professor

INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE (I.B.M.C.) / UPR-9002 DU CNRS, FRANCE

 

 

 

 

 

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