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FRCM ALGORITHM

FRCM: Flow-rate control module

 

  • Short settling time
  • Excellent flow stability
  • Predicts and automatically adjusts pressure
  • Control both pressure or flow-rate at will
FRCM ALGORITHMUS
  • The Flow Rate Control Module is a software solution dedicated to microfluidics and nanofluidics, based on an innovative algorithm that automatically controls pressures to reach a set flow-rate:
    • Fast and stable flow-rate control
    • Pressure actuated flow benefits with high-precision flow sensors
    • Much faster flow settling time and stability than syringe pumps
    • Useful for simple chip networks to parallel experiments and coupled systems.
    • Fast and stable flow-rate control
1. GET THE BEST RESULTS
  • Reach flow rate targets in less than 0.1 sec
  • Pulseless flow
2. CONTROL THE FLOW-RATE THE EASY WAY
  • Not sensitive to transient behaviors, including bubbles
  • Run experiments from minutes to over several days
  • Deals with external and internal perturbations (temperature drifts or clogging)
  • Permanently re-adjust its internal model
3. PERTURBATIONS WILL NO LONGER BE AN ISSUE
  • Minimizes cross-talk between channels
  • Immediately reacts to any perturbation
4. SAVE TIME WITH AN INTEGRATED SOFTWARE PACKAGE
  • Dedicated panel within MAESFLO™
  • Minimum and maximum flow-rate order limits
  • Bidirectional flow-rate on the same channel
FRCM ALGORITHMUS

Flow-rate, pressure and microfluidic resistance can be approximated by a simple equation, based on the electrical analogy (Ohm’s law). For a given applied pressure, the value of the flow-rate depends on the microfluidic design of the system.

So, as microfluidic designs become more and more complex, the calculation of the required pressure leading to the desired flow rate becomes more and more difficult. The case of coupled multi-channel chip designs for instance can be extremely difficult to address efficiently. The Flow Rate Control Module successfully overcomes these hurdles by predicting and automatically adjusting pressure(s) to reach the flow rate set-point(s).

Microfluidic resistance definiton ohm law

Indeed, the FRCM (Flow-Rate Control Module) is based on a powerful algorithm that enables the internal modeling of any microfluidic system linking each flow-rate to a combination of pressure orders, whatever the microfluidic design. Thanks to this unique algorithm, the FRCM can predict the pressure values to apply to reach the flow rate set-points.

FRCMPID
Controls “simple” microsystems, such as a single microchannel, as well as complex microfluidic systems, such as droplet generators, double encapsulation systems or mass parallel systems.Controls the flows in a single microchannel without any other flow junction.
  • Not sensitive to the transient behavior in the microsystems.
  • Providesstable behavior even if bubbles are present
  • Calculates a global solution (pressure to be applied) for the entire microsystem (tubing, microfluidic chip…)
  • Reduces the coupling effects between channel and the transient states.
  • Is very sensitive to any transient behavior.
  • The operating principle is based on a reaction to any deviation. This solution often leads to instable behavior in presence of bubbles in the microsystem.
  • Has to be tuned for each microsystems to be controlled, i.e. for each microchannel. As the tuning is long and sharp even for a “simple” system this solution seems to be irrelevant for complex systems.
  • As shown in the figure, applying pressure in the FLUIWELL™ reservoirs creates a liquid flow through a microsystem. As both pressures and flow-rates are measured by the MFCS™-EZ and the Flow-Rate Platform, the Flow-Rate Control Module is able to automatically adjust pressure(s) to reach the flow-rate set-point(s). This operating principle enables one to control flow-rates even in complex microsystems made of coupled channels and keep the benefit of pressure actuation.
Flow-rate control faq 1
  • The FRCM builds the internal model itself to determinate links between pressure and flow-rate
  • Flow-rate set-points are quickly entered in by the user via the MAESFLO™ software. Thanks to the internal model of the microfluidic experiment, the FRCM algorithm automatically calculates and applies the pressures needed to obtain the requested flow-rates.

P/N = FRCM-V1.1

icon questions

ANY QUESTIONS?

Of course, the chips can be ordered separately from the whole Droplet Starter Pack. We invite you to get in touch with our sales representatives or with your local distributor.

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Yes, the size market at the nozzle are here to help you estimate the size of the droplets you are generating. The Droplet Starter Pack has been designed to have very stable flow-rates, as the microfluidic resistance is mainly within the chip. This means that the flow-rates will stay stable even with pressure control only, thus the droplet sizes.

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